In den Texten zur Sorge und zu Sorgephänomenen (Sorge-Stress) weise ich auf die Tasache, dass Sorge die Lernfähigkeit begrenzt. Dazu:
Informationsdienst Wissenschaft - idw - Pressemitteilung Ruhr-Universität Bochum, Dr. Josef König, 04.06.2009 09:06
Einfach weitermachen ... RUB-Studie: Stress fördert gewohnheitsbasiertes Verhalten RUB-Forscher berichten im Journal of Neuroscience
Unter Stress spulen wir Gewohntes ab, egal ob es sinnvoll ist oder nicht. Zielgerichtetes Lernen hingegen wird durch Stress behindert. Das haben Bochumer Kognitionspsychologen um Dr. Lars Schwabe in einer Studie herausgefunden, die in der aktuellen Ausgabe des Journal of Neuroscience veröffentlicht ist. Lars Schwabe and Oliver T. Wolf: Stress Prompts Habit Behavior in Humans. In: Journal of Neuroscience, Stress Prompts Habit Behavior in Humans, J. Neurosci. 2009 29: 7191-7198; doi:10.1523/JNEUROSCI.0979-09.2009
An mehreren Stellen habe ich auf den Zusammenhang von Cortisol (siehe auch: Laborwerte) und Stress hingewiesen (auch im Zusammenhang mit Entzündungen und Hippocampusaktivitäten bei genuine Gefühlen). Hier nun ein neuer Beweis (sozusagen pars pro toto, stellvertretend für etliche andere Artikel):
Autor(en): Lyons DM, Buckmaster PS, Lee AG, Wu C, Mitra R, Duffey LM, Buckmaster CL, Her S, Patel PD, Schatzberg AF Titel: Stress coping stimulates hippocampal neurogenesis in adult monkeys. Journal: Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33): 14823-7. Bezug: Departments of Psychiatry and Behavioral Sciences, Stanford University Medical Center, Stanford, CA 94305, USA. dmlyons@stanford.edu Abstract: Coping with intermittent social stress is an essential aspect of living in complex social environments. Coping tends to counteract the deleterious effects of stress and is thought to induce neuroadaptations in corticolimbic brain systems. Here we test this hypothesis in adult squirrel monkey males exposed to intermittent social separations and new pair formations. These manipulations simulate conditions that typically occur in male social associations because of competition for limited access to residency in mixed-sex groups. As evidence of coping, we previously confirmed that cortisol levels initially increase and then are restored to prestress levels within several days of each separation and new pair formation. Follow-up studies with exogenous cortisol further established that feedback regulation of the hypothalamic-pituitary-adrenal axis is not impaired. Now we report that exposure to intermittent social separations and new pair formations increased hippocampal neurogenesis in squirrel monkey males. Hippocampal neurogenesis in rodents contributes to spatial learning performance, and in monkeys we found that spatial learning was enhanced in conditions that increased hippocampal neurogenesis. Corresponding changes were discerned in the expression of genes involved in survival and integration of adult-born granule cells into hippocampal neural circuits. These findings support recent indications that stress coping stimulates hippocampal neurogenesis in adult rodents. Psychotherapies designed to promote stress coping potentially have similar effects in humans with major depression.
Volltext-Artikel:
* HighWire Press PubMed-ID: 20675584 ISSN: 1091-6490 (Electronic)
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